The recognised effects of those PTMs on ATXN2’s perform and SCA2 pathogenesis continues to be minimal. In other polyQ conditions, several scientific studies proposed that proteolytic cleavage of polyQ proteins could Engage in a crucial function in pathogenesis [36, 45]. Aligned with this plan, the presence of the enriched 42 kDa https://barucha333rdn6.verybigblog.com/profile