The activation of CB1 and CB2 inhibits the development of intracellular cAMP, therefore leading to a tremendous reduction of the excitatory effect within the neurons [88,89]. In addition, the activation of CB2 can further more avert the mast cell degranulation and the release of pro-inflammatory mediators, making the reduction https://conolidine24555.getblogs.net/59236428/fascination-about-block-pain-receptors-with-proleviate